1) In the articles published in ‘Kerala Kaumudi’, ‘Manorama’, ‘The Hindu’ and various other media sources, this doctor brothers claimed of having secured more than 100 patents in various countries.
If they know that they have only submitted few (~10) patents in India (that also needede to be verified!), why they have made such claims? I think they also know that ‘patents’ are only valid if they are approved. Anybody can apply for a patent with trivial ideas !!! Were they trying to fool the media and the public, taking the advantage of the lack of more information on ‘nanotechnology’?
2) In reports published in various media sources, these doctor brothers claimed of having invented a ‘nano chip’ called ‘nanogene seq’, which can sequence the entire human genome in less than 2 hours with 99% accuracy for a cost of less than 3000 rupees. Even they told some websites that the product is just few months away from commercialization after fine tuning. Recently in ‘Mathrubhumi’ report they confessed that all their ‘nanotechnology’ based inventions are in the logical (fraud!) level only (none of them are real developed products). Then why they claim like this before? Is it to confuse media and public about their inventions? Then from where they got these statistics like 99% accuracy, cost of Rs. 3000 and less than 2 hours processing time? All from their imagination or dreams?
3) They are claiming that they have been doing research in nanotechnology from their college days. If that is true,
(i) What are their practical experiences in this field other than reading and formulating trivial and broken ideas with the help of a computer and internet? Did they do any ‘nanotechnology based research project’ or got any sort of ‘training in this field’ from any institution in India or Abroad during this period?
(ii) Do they have some reference (any scientific personality) who can certify (and support) their experience or proficiency in the ‘nanotechnology’ field other than the so called ‘Encouragement Letters’ from US President or Microsoft Chairman?
(iii) If they have formulated these inventions with the help of scientific institutions at Trivandrum (as they had claimed earlier), which are the institutions helped them with their projects? Any scientific support/reference from these institutions?
(iii) Do they have any ‘scientific publication’ or ‘approved patent’ to prove their claims?
(iv) What evidence do they have in support of their inventions such as ‘nanogene seq’ chip? Did they present it in front of some scientific body and got some feed back? Did they try to demonstrate the feasibility of their idea by any chance? What about their willingness to present these concepts/ideas (of their claimed inventions) before a ‘scientific panel’ constituting experts from various institutions at Trivandrum?
4) What about the ‘novelty’ of their ideas? Most of them are trivial and are badly copied from internet (thanks to Google!). Do they still believe will somebody issue patents for such trivial ideas?
(i) For example their most important ‘idea invention’ (‘nanogene seq’ chip) is just an Indian version of a flawed idea of a Harvard medical school dropout named Eugene Chan who dreamed of making a nanochannel based ‘gene machine’, which can sequence the entire DNA 1000-2000 times faster than the conventional techniques. After forming a company (US Genomics) and wasting 60-70 million dollars (~300 crore rupees), he has to step down without achieving that goal !!!
(ii) Most of the ideas they coined in the proposal (like developing nanomedicine, nanorobots etc) are also known to the scientific world for years. What is their novel contribution to this?
(iii) Another claim is that ‘they have developed’ a ‘genetic horoscope’ idea based on their ‘nano chip’. Do they think that, it is a new idea that if you know the entire human genome of an individual and the genes corresponding to each genetic behavior (which is still a dream for scientists) we can predict the ‘genetic related’ future of an individual? It will be a surprise to the scientific community if these doctors claim of first time introducing the idea of ‘personalized medicine’ and ‘gene therapy’ from their inventions. Are they that foolish to claim such widely debated and researched areas/ideas to their credit? Ever since the discovery of the structure of DNA it is known that DNA is responsible for the hereditary behaviour, and it’s a middle school science topic. What is the novelty in their ‘genetic horoscope’? Old wine in a new bottle with an attractive label !!! What about the needed 'genomics' and 'proteomics' research bsupport for this? Do they develop that also?
(iv) Do they still believe that their ‘nano chip’ (once it is made real !!!) can identify the possibility of viral disease like AIDS? Or else what do their invention has to do with AIDS according to their claims? Are they naive to think that they can trace out all diseases with a known ‘genetic code’? Do they know the difference between genetic diseases and others (of course they should as they are medical doctors !!!). Then why is such confusing jargons?
5) The only demand of their critics (in terms of scientific claims and proposals, not their personal life !!!), is a ‘scientific level’ investigation on their claims and ‘scientific credibility’ for the present proposal. How they react to this demand? Are they confident to prove their content before a scientific committee since they have "patents" for all those?
The press may give emphasis to this point to have a ‘scientific level investigation’ on their claims and a re-evaluation of the entire proposal. Thus we can purify this noble science venture from possible errors/draw backs !!!